‌Julia Dallman

ASSOCIATE PROFESSOR

View CV

003 Cox Science Center
1301 Memorial Drive, Coral Gables, FL 33146
E-mail: jdallman@bio.miami.edu
Office: (305) 284-3954

Link to Dallman Lab


EDUCATION AND PROFESSIONAL EXPERIENCE

  • 2016-Present, Associate Professor, University of Miami, Department of Biology
  • 2010, Director of University of Miami Zebrafish Facility
  • 2007-2016, Assistant Professor, Univeristy of Miami, Department of Biology
  • 2005, Co-lecturer Comparative Invertebrate Embryology(Zool. 536) Friday Harbor Laboratories, University of Washington
  • 2003-2007, Research Assistant Professor, Dept. of Neurobiology, SUNY Stony Brook, NY Mentor: Dr. Paul Brehm
  • 1998-2003, Postdoctoral Fellow, Dept. of Neurobiology, SUNY Stony Brook, NY Mentor: Dr. Gail Mandel
  • 1991-1998, Ph.D. from the Dept of Zoology, University of Washington, Seattle, WA Mentor: Dr. William J Moody
  • 1987-1991, BA from the Dept. of Biology, Swarthmore College, Swarthmore, PA
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AWARDS

  • 2016, NIH Profiled as Success Story by NINDS (Link)
  • 1998-2000, NIH Individual National Research Service Award
  • 1995-1997, NSF Mathematical Biology Trainee
  • 1991-1994, NIH Molecular and Cellular Biology Trainee

GRANTS

  • 2014-2106, NIH R03 (PI Dallman, JE); Stable Zebrafish Mutant Models of Autism Spectrum Disorder.” 
  • 2012-2017, NIH R01 (PI Tekin, M; CoI J. Dallman) “Genetic Studies of Inner Ear Anomalies”
  • 2012-2017, NIH R01 (PIs Michael Shy, MD and Stephan Zuchner, MD; CoI Julia Dallman) “Genomic Studies in Charcot-Marie-Tooth Disease.”
  • 2012 Muscular Dystrophy Association Grant (PI Stephan Zuchner CoI Julia Dallman) “Gene identification in axonal CMT families.”
  • 2012, Hope for Vision,  Advances and future directions in the understanding of autosomal recessive Retinitis Pigmentosa.
  • 2012-2013, NIH, National Institutes of Neurological Disease and Stroke, The Genetics of Parkinsonism (PI: Vance, JM' CoI, J. Dallman)
  • 2009, NIH ARRA funds to J. Dallman; undergraduate summer stipends
  • 2004-2008, Principal Investigator NIH K01 Career Development Award

AREAS OF FOCUS

Development and Neuroscience


RESEARCH INTERESTS

Determining the mechanisms by which genes influence behavior is the central goal of my research program.  The genome-sequencing revolution has identified thousands of genetic mutations that cause neurological disorders that impact human behavior.  For any given disorder, mutations in hundreds of different genes can similarly affect behavior, and yet how these disparate mutations converge on similar behavioral phenotypes is largely unknown.  To address this question, my group generates zebrafish models of inherited human behavioral disorders to understand how mutations impact neural circuit development and behavior.  By comparing multiple forms of a single disorder, we elucidate shared mechanisms by which different mutations affect behavior.  Our long-term goal is to leverage these models to inform treatment strategies for individuals with inherited disorders of the nervous system.

 


TEACHING INTERESTS

My goals in the classroom are not only to pass on information but also to convey my own excitement about the material as a means of encouraging students to think critically about the topics we cover. My aim is to make the students active participants in their learning. I also expose students to the primary literature and discuss the methods employed by the researchers so that the process by which we understand biological systems becomes apparent.


SELECTED PUBLICATIONS

  • Yan Q, Zhai L, Zhang B, & Dallman JE. (2017) Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development. J. Comp. Neurol. 525(7):1649-1667.

    Prince JS, Dallman JE, Miyazaki S, Wen R. (2016) Ultrastructural Analysis of Zebra Fish (Daniorerio) DHDDS Retinitis Pigmentosa Disease Model Functionally Links DHDDS to Mitochondrial and Membrane Dysfunction.  American International Journal of Biology 4(2):39-51.

    Li S, Skromne I, Peng Z, Dallman J, Al-Youbi AO, Bashammakh AS, El-Shahawi MS, and Leblanc RM. (2016) “Dark” Carbon Dots Specifically “Light-up” Calcified Zebrafish Bones. J. Mat. Chem. B DOI: 10.1039/C6TB02241C

    Kozol RA, Abrams AJ, James DM, Buglo E, Yan Q, & Dallman JE. Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish.  Frontiers in Molecular Neuroscience 2016.00055:Research Topic: Molecular, cellular and model organism approaches for understanding the basis of neurological disease.

    Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez M, Campeanu J, Griffin L, Groenewald S, Strickland A, Tao F, Speziani F, Caporali L, Ahmed ZM, Sund KL, Wang X, Krueger LA, Peng Y, Prada CE, Prows CA, Bove K, Schorry EK, Antonellis A, Zimmerman HH, Abdulrahman OA, Yang Y, Downes S, Prince J, Nemeth A, Carelli V, Huang T, Züchner S, Dallman JE. (2015) Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nature Genetics 47(8): 928.

    Kozol RA, Cukier HN, Mayo V, Griswald AJ, Whitehead PL, Haines JL, Gilbert JR, Cuccaro ML, Martin ER, Baker JD, Buxbaum JD, Pericak-Vance MA, Dallman JE. (2015) Two zebrafish autism models of SYNGAP1 and SHANK3 knock-down produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis. Human Molecular Genetics 24(14):4006-23.

    Ganser LR, Yan Q, James VM, Kozol R, Topf M, Harvey RJ, and Dallman JE. (2013) Distinct phenotypes in zebrafish models of human startle disease. Neurobiology of Disease 60:139-51.

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